How does HIV contribute to the development of certain cancers?

The selected answer highlights a crucial mechanism through which HIV is implicated in the development of certain cancers. HIV primarily weakens the immune system by attacking and depleting CD4+ T cells, a vital component of the immune response. As a result of this immune suppression, the body becomes less capable of identifying and eliminating abnormal cells, which can include precancerous or cancerous formations. Without an effective immune response to monitor and manage cellular abnormalities, individuals living with HIV have an increased risk of developing various types of cancers, particularly those associated with viral infections like Kaposi's sarcoma, non-Hodgkin lymphoma, and invasive cervical cancer.

While other options address mechanisms like direct causation or alterations to DNA, they do not accurately reflect the primary role of HIV in cancer development. Although HIV itself might not directly transform healthy cells into cancerous ones or introduce carcinogens, the compromised immune function due to HIV is the key factor that elevates the risk of cancer in affected individuals. This understanding underscores the importance of continuous monitoring and prevention strategies for individuals with HIV to mitigate potential cancer risks.