How can an HIV-negative person reduce their risk of contracting HIV?

An HIV-negative person can significantly reduce their risk of contracting HIV by utilizing pre-exposure prophylaxis (PrEP) in combination with practicing safer sex methods. PrEP is a highly effective medication for individuals at high risk of HIV exposure; when taken consistently, it can lower the risk of getting HIV from sex by about 99%.

In addition to medication, practicing safer sex methods, such as using condoms, can provide further protection. This dual approach addresses both the potential for exposure during sexual activity and the pharmacological prevention offered by PrEP, making it a comprehensive strategy against HIV transmission.

Other approaches, while beneficial in certain contexts, may not provide the same level of protection. Using condoms exclusively, for instance, can reduce risk, but it does not eliminate it completely; improper use or breakage can occur, leading to potential exposure. Limiting sexual partners to one can also reduce risk but does not account for the partner's HIV status or other factors affecting transmission. Lastly, avoiding intimate relationships altogether eliminates the risk, but this isn't a practical or feasible lifestyle choice for many individuals. Thus, the combination of PrEP and safer sex practices forms the most effective strategy for reducing the risk of HIV infection.